Strengthening Systemic Health, Starting from the Mouth

GLAC Biotech's Totipro® Postbiotics PE0301 is a synergistic blend of three proprietary strains: Lactobacillus salivarius AP-32, Lactobacillus plantarum LPL28, and Lactobacillus paracasei ET-66. It is expertly formulated to inhibit a wide range of oral pathogens, balance the oral microbiome, and fortify the upper gastrointestinal (GI) tract's first line of defense, thereby enhancing overall systemic immunity.

The oral cavity serves as the body's primary gateway and first line of defense. When pathogens invade the upper GI tract and disrupt the delicate oral microbiome, it can trigger a cascade of systemic health issues. Research shows the mouth is home to over 600 species of bacteria. Many of these, including harmful pathogens, can travel with saliva down the digestive tract, impacting the entire body. This imbalance is not just a local issue; it's increasingly linked to systemic diseases, and has even been associated with malignant tumors and cognitive decline, including the onset or worsening of conditions like Alzheimer's disease.

An Imbalanced Oral Microbiome Can Lead To:

• Increased Susceptibility to Infections: Greater vulnerability to viral and seasonal illnesses.

• Frequent Oral Health Issues: Higher incidence of cavities, gum disease, and canker sores.

• Increased Risk of Chronic Illnesses: Can contribute to nutritional deficiencies and metabolic conditions like diabetes.

• Systemic Health Complications: Pathogens breaching the upper GI defense can trigger other internal diseases.

• Worsening of Major Illnesses: Harmful bacteria colonizing the body can exacerbate serious conditions.

• Cognitive Decline: Severe oral disease is now linked to a higher risk of dementia.

Recognizing that a compromised upper GI tract can trigger systemic health failures, GLAC Biotech developed Totipro® Postbiotics PE0301—the first postbiotic expertly formulated to resolve health issues caused by microbiome imbalance.

Clinically shown to inhibit multiple oral pathogens, including those responsible for cavities and gum disease, PE0301 helps restore a healthy balance to the oral microbiome. Its high stability and compliance with food safety standards make it an ideal ingredient for boosting the upper GI tract's population of beneficial bacteria and strengthening the body's overall health defenses.

Key Benefits and Features

1. Supports Upper GI Comfort and Immunity: Alleviates symptoms of acid reflux, indigestion, and general stomach discomfort. It helps reduce the colonization of harmful bacteria, lowering the risk of chronic illness and enhancing internal immunity.

2. Reinforces Oral Defenses: Boosts Immunoglobulin A (IgA) levels in saliva, promotes the growth of beneficial oral bacteria, and effectively helps reduce the occurrence of canker sores and oral abscesses.

3. Advanced Synergistic Formula: This multi-strain blend balances the oral microbiome and supports gum health, which in turn may help protect against the development of neurodegenerative diseases.

4. Natural and Efficacious: Made with natural ingredients and backed by comprehensive safety reports for complete peace of mind.

5. Proven Safe for Systemic Health: Verified to be safe and non-toxic through five major toxicological safety assessments, ensuring double protection for the entire body.

6. Highly Stable & Versatile for Product Application: Exceptional heat and bile salt stability allows for broad application across various final product formats.

Advanced Manufacturing Technology

Totipro® PE0301 is manufactured using GLAC's proprietary PRONEX® technology. This includes our p-coretex™ high-density fermentation and patented HeaLAC® postbiotic process. Our fully automated, computer-controlled system eliminates human error and locks in a high concentration of beneficial metabolites, ensuring the standardized, high-quality mass production of an international-grade ingredient.

In summary, Totipro® Postbiotics PE0301 is GLAC Biotech’s premier solution for upper GI health. Its multi-strain formula delivers superior efficacy compared to single-strain ingredients, providing a comprehensive boost to the body's defenses. With its exceptional stability, it is the ideal postbiotic for a wide variety of consumer product applications.

Your Expert Partner in Upper GI Solutions

As specialists in upper GI solutions, GLAC Biotech offers more than just postbiotics. Our portfolio also includes probiotics (live bacteria) and inactivated strains (such as L. salivarius AP-32 and L. paracasei ET-66), perfect for tablet formulations and other custom solutions for oral and digestive health.

To learn more about our postbiotics and end-product manufacturing opportunities, contact us