HOME > > Products > PRONULIFE® (Probiotic) > PRONULIFE®NosRelieve/BabyAllieve
PRONULIFE®NosRelieve/BabyAllieve
Immune-Support Probiotic Solutions for Adults and Infants — starting from the gut
Why start with the gut?
Up to 70% of immune cells are associated with the gut, underscoring the gut as the body’s largest immune organ. The intestinal microbiota influences not only digestive comfort but also the integrity of the body’s immune barrier.
Environmental factors and family history are both linked with seasonal sensitivity. For example, air quality (e.g., nitrogen oxides, carbon monoxide) is associated with respiratory discomfort. Reports also indicate that when one parent has an atopic tendency, a child’s likelihood of showing related sensitivity is around 30%; when both parents share the same tendency, the child’s risk can reach ~70%.
For everyday immune management, the gut is a smart place to begin.
How do probiotics support immune balance?
Clinically researched formulation design
PRONULIFE® NosRelieve (Adult Formula)
Technology advantages — built for stability & consistency
* MP137 / MP108 are market-specific strains and are available outside Taiwan only.
Patents
Why Glac?
Beyond premium ingredients, Glac provides end-to-end support from R&D and formulation design to regulatory guidance, helping partners:
✅ Shorten development timelines
✅ Lower development barriers
✅ Build market competitiveness and consumer trust
📩 For technical data, customization inquiries, or formulation partnerships, contact us at
📧 glac@glac.com.tw
Further Reading: PRONULIFE® Functional Probiotic Ingredients🔙
Key References
Why start with the gut?
Up to 70% of immune cells are associated with the gut, underscoring the gut as the body’s largest immune organ. The intestinal microbiota influences not only digestive comfort but also the integrity of the body’s immune barrier.
Environmental factors and family history are both linked with seasonal sensitivity. For example, air quality (e.g., nitrogen oxides, carbon monoxide) is associated with respiratory discomfort. Reports also indicate that when one parent has an atopic tendency, a child’s likelihood of showing related sensitivity is around 30%; when both parents share the same tendency, the child’s risk can reach ~70%.
For everyday immune management, the gut is a smart place to begin.
How do probiotics support immune balance?
- Modulating immune cell activity: Interaction with antigen-presenting cells (APCs) such as macrophages and dendritic cells helps support systemic immune regulation.
- Multi-axis support: Via the gut–lung, gut–skin, and gut–brain axes, probiotics help maintain everyday respiratory and skin wellness.
- Balancing responses: Literature suggests specific strains can support Treg/Th1 activity and balance Th2, helping reduce the risk of over-responses.
- Maintaining the mucosal barrier: A well-supported gut helps maintain barrier function and resilience to external stressors.
- Aiding digestion & absorption: A balanced microbiota supports nutrient absorption and gastrointestinal comfort, contributing to everyday immune support.
Clinically researched formulation design
PRONULIFE® NosRelieve (Adult Formula)
- In 12-week evaluations, participants reported improvements in seasonal nasal comfort
- Concurrent trends included down-regulation of IL-4, sIgE, and T-IgE, consistent with everyday immune-support aims.
- Skin-related readouts in certain studies also showed subjective improvement alongside IgE changes.
- A multi-strain design tailored for infants/children.
- Under specific study conditions, observations included subjective improvements in skin comfort and seasonal sensitivity markers.
Technology advantages — built for stability & consistency
- Multi-strain synergy: NosRelieve and BabyAllieve select Lactobacillus strains to focus on gut microbiome balance and immune support.
- PRONEX® micro-encapsulation: Helps preserve stability and lot-to-lot consistency during storage and use.
- IP & evidence base: Global patent portfolio plus peer-reviewed and clinical data support professional trust and B2B communications.
| Ingredients | Probiotic Blend | Application Focus |
| PRONULIFE® NosRelieve | L. reuteri GL-104 L. paracasei GL-156 L. rhamnosus MP108* | Seasonal nasal comfort and upper-respiratory wellness support |
| PRONULIFE® BabyAllieve | L. reuteri GL-104 L. rhamnosus F-1 L. paracasei MP137* L. rhamnosus MP108* | Skin comfort for sensitive skin and seasonal wellness support in children |
Patents
- TW I355272 | Food/pharma compositions with novel lactic acid bacteria strains for allergy-related management
- CN102309001B | Food/pharma compositions with novel lactic acid bacteria strains for allergy-related management
- TW I451871 | Food/pharma compositions with lactic acid bacteria for suppressing inflammatory responses
- CN102835657B | Food/pharma compositions with lactic acid bacteria for suppressing inflammatory responses
- US9011839B2 | Food/pharma compositions with lactic acid bacteria for suppressing inflammatory responses
- CN103550258B | Use of probiotic strains to regulate immune responses
- CN102604854B | Application of novel probiotic strains and their role in regulating immune responses
- CN103436461B | Application of novel probiotic strains and their role in regulating immune responses
- TW I429444 | Application of novel probiotic strains and their role in regulating immune responses
Why Glac?
Beyond premium ingredients, Glac provides end-to-end support from R&D and formulation design to regulatory guidance, helping partners:
✅ Shorten development timelines
✅ Lower development barriers
✅ Build market competitiveness and consumer trust
📧 glac@glac.com.tw
Further Reading: PRONULIFE® Functional Probiotic Ingredients🔙
Key References
- Lactobacillus reuteri GL-104 for modulation in allergy. International Symposium on Lactic Acid Bacteria. 2010:25–27.
- Potential of probiotic strains to modulate inflammatory responses of epithelial and immune cells in vitro. New Microbiol. 2013;36(2):167–179
- Clinical observation of active probiotics in the treatment of allergic rhinitis and its immunoregulatory effects. China Modern Doctor. 2017;55(5):66–68
- Early application of lactobacillus tetravaccine in preventing allergic diseases of infants. Practical Journal of Clinical Medicine. 2018;15(4):71–73.
